Been out of the lab for a few years now, but I was still pipette in hand when CAR T was starting making a big splash. I honestly think the sky is the limit for CAR T therapy, progress has been so rapid in the last decade! I'd love to see one of two things happen: figure out how to have an immortalised cell line that works like a 'universal donor' and then just CRISPR away with that OR find a way to retain the benefits of immortalised CAR T but as a cell-free approach. For all I know all this stuff has been done already (sorry if you've linked to it). I also reckon there's huge potential for anti-aging treatment too... If that doesn't get the big bucks rolling in, nothing will!
Thank you so much for this and the explanation so that non-scientists like myself can understand. We have the scientists we just need to fund their research, it is so important!
Been out of the lab for a few years now, but I was still pipette in hand when CAR T was starting making a big splash. I honestly think the sky is the limit for CAR T therapy, progress has been so rapid in the last decade! I'd love to see one of two things happen: figure out how to have an immortalised cell line that works like a 'universal donor' and then just CRISPR away with that OR find a way to retain the benefits of immortalised CAR T but as a cell-free approach. For all I know all this stuff has been done already (sorry if you've linked to it). I also reckon there's huge potential for anti-aging treatment too... If that doesn't get the big bucks rolling in, nothing will!
Thank you so much for this and the explanation so that non-scientists like myself can understand. We have the scientists we just need to fund their research, it is so important!